The transcription factor nuclear factor Y regulates the proliferation of myeloid progenitor cells
نویسندگان
چکیده
منابع مشابه
The transcription factor nuclear factor Y regulates the proliferation of myeloid progenitor cells.
The transcription factor nuclear factor Y (NF-Y) consists of three subunits; NF-YA, -B and -C, and this complex binds DNA and the basal transcription machinery through binding of TBP. NF-Y targets include cell cycle related genes and hematopoietic (stem) cell genes such as cd34 and hoxb4. Deletion of both nf-ya alleles in mice results in embryonic lethality. Inactivation of NF-YA in mouse embry...
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ژورنال
عنوان ژورنال: Haematologica
سال: 2008
ISSN: 0390-6078,1592-8721
DOI: 10.3324/haematol.12425